Found 11 matching trials
Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults
PHASE1This is a randomized, double blind, placebo-controlled, single site, trial ...
Location
Fred Hutchinson Cancer Research Center
VAC071: A Study to Assess Efficacy of the ChAd63/MVA PvDBP Vaccines
PHASE2This is an open label, Phase IIa, controlled human malaria infection (CHMI)...
Location
Centre for Clinical Vaccinology & Tropical Medicine
Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous Infection
NAMalaria, a disease caused by the parasite Plasmodium, is one of the world's...
Location
Radboud university medical center
Safety and Efficacy of NF135 CPS Immunization
NAThis is an open label, randomized, controlled clinical trial. The primary a...
Location
Radboud university medical centre
Controlled Human Malaria Infection (CHMI) After Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis
PHASE1The purpose of the study is to determine the safety and tolerability of ID ...
Location
Radboud University Nijmegen Medical Centre
A Study to Assess the Immunogenicity, Tolerability and Safety of a Malaria Vaccine and Also Its Protective Efficacy in a Malaria Challenge Model
PHASE1The purpose of this study is to assess the safety, tolerability and immunog...
Location
Malaria Clinical Trials Center at Seattle Biomedical Research Institute
A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMI
PHASE1USSPZV7 is a randomized, phase 1, double-blind, placebo-controlled trial of...
Location
University of Maryland, Baltimore, Center for Vaccine Development and Global Health
Dose Escalation PfSPZ-CVac
PHASE1Background:
People get malaria from bites from infected mosquitos. Researc...
Location
National Institutes of Health Clinical Center
PfSPZ Vaccine: Dose Optimization With Heterologous Challenge in Healthy Malaria-Naïve Adults
PHASE2This is an open-label evaluation of the safety, tolerability, immunogenicit...
Location
University of Maryland-Baltimore, Center for Vaccine Development
Re-exposure of Human Volunteers to a Heterologous Strain of P. Falciparum Sporozoites
NAIn a previous study (NL33904.091.10) the investigators challenged 24 volunt...
Location
Leiden University Medical Centre